Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080382 | 0.95 | CYP4F2 (0.46) | TDP1SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3096179 | 0.91 | SLC7A5 (0.47) | TDP1SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3087849 | 0.88 | ALDH1A1 (0.49) | TDP1SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3098923 | 0.86 | TDP1 (0.44) | TDP1CYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL1475118 | 0.86 | TDP1 (0.62) | TDP1SLC7A5CYP4F2CYP4A11LMNA | |
| SCHEMBL3096166 | 0.84 | SLC7A5 (0.48) | TDP1SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1474816 | 0.84 | TDP1 (0.61) | TDP1SLC7A5CYP4F2CYP4A11LMNA | |
| SCHEMBL11723807 | 0.83 | TDP1 (0.62) | TDP1SLC7A5CYP4F2CYP4A11LMNA | |
| SCHEMBL3098911 | 0.83 | TDP1 (0.44) | TDP1CYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL3087844 | 0.82 | ALDH1A1 (0.50) | SLC7A5CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799892-B2 | Method of making polybutylene terephthalate and compositions and articles comprising the same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-09-21 | — | — | US | claimed |
| US-20090275698-A1 | Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-11-05 | — | — | US | claimed |
| US-7799892-B2 | Method of making polybutylene terephthalate and compositions and articles comprising the same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-09-21 | — | — | US | disclosed |
| US-20090275698-A1 | Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-11-05 | — | — | US | disclosed |