Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.39 |
| ▸ | WNT1 | P04628 | 5/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804510 | 0.88 | CDC7 (0.51) | EGFRMAPK1CDC7DYRK1AWNT1 | |
| SCHEMBL27092617 | 0.77 | KAT2B (0.42) | KAT2BEGFRPGK1TLR9 | |
| SCHEMBL27199808 | 0.76 | PGK1 (0.40) | KAT2BEGFRPGK1TLR9SLC2A1 | |
| SCHEMBL31356297 | 0.76 | CHEK1 (0.44) | KAT2BEGFRPGK1TLR9 | |
| SCHEMBL10830932 | 0.75 | MAPK10 (0.56) | KAT2BMAPK10SLC2A1 | |
| SCHEMBL20901592 | 0.72 | GRM4 (0.42) | MAPK1 | |
| SCHEMBL11147779 | 0.72 | KAT2B (0.54) | KAT2BMAPK10CDC7 | |
| SCHEMBL10831286 | 0.72 | KAT2B (0.54) | KAT2BMAPK10CDC7 | |
| SCHEMBL31485516 | 0.72 | CHEK1 (0.40) | KAT2BEGFRPGK1TLR9SLC2A1 | |
| Hydrochloric Acid SCHEMBL10831715 | 0.71 | KAT2B (0.53) | KAT2BMAPK10CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583977-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052512-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | WO | disclosed |