Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065790 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL29445081 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL30805793 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL4106122 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL5194206 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL31472070 | 0.87 | TDP1 (0.53) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL5274508 | 0.85 | TDP1 (0.56) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL14833236 | 0.85 | TDP1 (0.59) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL29445097 | 0.85 | TDP1 (0.59) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL4910827 | 0.85 | TDP1 (0.59) | TDP1LMNAALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032755-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024032776-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2024-02-15 | — | — | WO | disclosed |