Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805802 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL29445081 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL30805793 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL4106122 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL5194206 | 1.00 | TDP1 (0.62) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL31472070 | 0.87 | TDP1 (0.53) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL5274508 | 0.85 | TDP1 (0.56) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL14833236 | 0.85 | TDP1 (0.59) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL29445097 | 0.85 | TDP1 (0.59) | TDP1LMNAALDH1A1HTTGAA | |
| SCHEMBL4910827 | 0.85 | TDP1 (0.59) | TDP1LMNAALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885340-B1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORP (FI) | 2024-11-27 | — | — | EP | disclosed |
| EP-3885340-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2021-09-29 | — | — | EP | disclosed |
| US-11046713-B2 | Androgen receptor modulating compounds | ORION CORPORATION (FI) | 2021-06-29 | — | — | US | disclosed |
| EP-3369732-B1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORP (FI) | 2021-05-26 | — | — | EP | disclosed |
| US-20200299307-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORP (FI) | 2020-09-24 | — | — | US | disclosed |
| US-10711013-B2 | Androgen receptor modulating compounds | ORION CORPORATION (FI) | 2020-07-14 | — | — | US | disclosed |
| US-20190100536-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORP (FI) | 2019-04-04 | — | — | US | disclosed |
| US-10118933-B2 | Androgen receptor modulating compounds | ORION CORPORATION (FI) | 2018-11-06 | — | — | US | disclosed |
| EP-3369732-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2018-09-05 | — | — | EP | disclosed |
| US-20170260206-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORP (FI) | 2017-09-14 | — | — | US | disclosed |
| US-20060178425-A1 | FUNGICIDAL CARBOXAMIDES | BASARAB GREGORY S | 2006-08-10 | — | — | US | disclosed |
| US-20050245529-A1 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | US | disclosed |
| US-6683212-B1 | N-(1-(2-NAPHTHALENYL)ETHYL)CYCLOBUTANECARBOXAMIDE DERIVATIVES; PLANT DISEASES; CROPS; AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-01-27 | — | — | US | disclosed |
| US-6642392-B1 | Pyrrole derivatives | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-11-04 | — | — | US | disclosed |
| US-20030191189-A1 | Fungicidal amides | BASARAB GREGORY S (US) | 2003-10-09 | — | — | US | disclosed |
| US-6504058-B1 | (1(R)-cis)-3-chloro-1,3-dimethyl-N-(1-(2-napthalenyl)ethyl) -cyclobutanecarboxamide and/or isomers, used for controlling plant diseases caused by fungi | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-01-07 | — | — | US | disclosed |
| US-6251947-B1 | CERTAIN N-(ARYLPROPYL), N-(ARYLOXYETHYL), AND N-(ARYLALLYL)-CARBOXAMIDES, THEIR AGRICULTURALLY SUITABLE SALTS USED AS FUNGICIDE TO CONTROL PLANT DISEASE BY APPLYING AN EFFECTIVE AMOUNT ON THE PLANT | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2001-06-26 | — | — | US | disclosed |
| EP-0165110-B1 | OPTICALLY ACTIVE ISOCARBOSTYRIL DERIVATIVES AND A METHOD OF PREPARING THE SAME | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-12-28 | — | — | EP | disclosed |
| US-4659833-A | FOUR OPTICAL ISOMERS OF 1-(2'-(O-METHOXYPHENYL)-1'-METHYLETHYLAMINO)-3-(4\"-ISOCARBOSTYRILOXY)-2 -PROPANOL ISOLATED BY LIQUID CHROMATOGRAPHY | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0165110-A1 | Optically active isocarbostyril derivatives and a method of preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260206-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | AR, NR5A1, SHBG | TDP1 3907/4885LMNA 4479/4885ALDH1A1 570/4885 |
| US-10118933-B2 | Androgen receptor modulating compounds | AR, NR5A1, SHBG | TDP1 3907/4885LMNA 4479/4885ALDH1A1 570/4885 |
| US-10711013-B2 | Androgen receptor modulating compounds | AR, NR5A1, SHBG | TDP1 3907/4885LMNA 4479/4885ALDH1A1 570/4885 |
| US-20200299307-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | AR, NR5A1, SHBG | TDP1 3907/4885LMNA 4479/4885ALDH1A1 570/4885 |
| US-20190100536-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | AR, NR5A1, SHBG | TDP1 3907/4885LMNA 4479/4885ALDH1A1 570/4885 |
| US-11046713-B2 | Androgen receptor modulating compounds | AR, NR5A1, SHBG | TDP1 3907/4885LMNA 4479/4885ALDH1A1 570/4885 |
| US-20060178425-A1 | FUNGICIDAL CARBOXAMIDES | CBR3, CBR1, CYC1 | TDP1 877/4885LMNA 1695/4885ALDH1A1 1188/4885 |
| US-20050245529-A1 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, GPR119, MCHR2 | TDP1 4642/4885LMNA 2541/4885ALDH1A1 3033/4885 |
| US-20030191189-A1 | Fungicidal amides | CBR1, CBR3, CYCS | TDP1 1227/4885LMNA 3409/4885ALDH1A1 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.