SCHEMBL3080652

SCHEMBL3080652

Cc1cc(O)ccc1-c1nnc(-c2ccc(C(C)(C)C)cc2)o1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.53
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 1/20 0.50
GUSB P08236 8/20 0.46
S1PR4 O95977 1/20 0.46
S1PR5 Q9H228 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TSHR P16473 3/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NR1H4 Q96RI1 1/20 0.44
ESR1 P03372 1/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL969124 0.83 KDM4E (0.64) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL4017705 0.83 KDM4E (0.64) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL969333 0.82 S1PR1 (0.58) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL669171 0.82 S1PR1 (0.61) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL18741407 0.82 KDM4E (0.62) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL2653612 0.80 ESR2 (0.61) TSHRESR1
SCHEMBL966175 0.79 KDM4E (0.58) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL3089482 0.79 MAPT (0.49) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL966614 0.78 NPC1 (0.54) S1PR1NPC1RAB9AKDM4EALDH1A1
SCHEMBL967890 0.78 NPC1 (0.54) S1PR1NPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258804-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2012-08-22 EP disclosed
EP-2258804-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2010-12-08 EP disclosed
US-7795802-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2010-09-14 US disclosed
US-7365141-B2 Solvent resistance; luminescent film-forming solvent processible polymer which contains cross-linking so as to increase its molar mass and to resist solvent dissolution, the cross-linking being such that the polymer retains semiconductive and luminescent properties; capable of charge transport CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2008-04-29 US disclosed
EP-1801181-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2007-06-27 EP disclosed
EP-1715021-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
EP-1715020-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
US-20050282983-A1 Crosslinking a luminescent film forming solvent processible polymer; solvent resistance; semiconductive polymers CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2005-12-22 US disclosed
US-6919415-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2005-07-19 US disclosed
EP-1006169-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2004-11-03 EP disclosed
US-6723811-B1 PHOTOLUMINESCENT AND ELECTROLUMINESCENT DEVICES; SEMICONDUCTOR POLYMER; ORGANIC LED; CROSSLINKING TO MAKE INSOLUBLE CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-04-20 US disclosed
US-20040059077-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-03-25 US disclosed
US-6559256-B2 Luminescent film-forming solvent processible polymer for use in photoluminescent and electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-05-06 US disclosed
EP-1291406-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2003-03-12 EP disclosed
US-20030008991-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-01-09 US disclosed
EP-1006169-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2000-06-07 EP disclosed