SCHEMBL3089482

SCHEMBL3089482

CC(=O)Oc1ccc(-c2nnc(-c3ccc(C(C)(C)C)cc3)o2)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
S1PR1 P21453 2/20 0.46
NR1H4 Q96RI1 1/20 0.44
S1PR4 O95977 1/20 0.43
S1PR5 Q9H228 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TP53 P04637 3/20 0.42
PTPN1 P18031 1/20 0.42
IKBKB O14920 1/20 0.41
PKM P14618 1/20 0.41
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
ABCG2 Q9UNQ0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL968443 0.86 RAB9A (0.53) MAPTKDM4EALDH1A1S1PR1NR1H4
SCHEMBL3666640 0.83 NR1H4 (0.49) MAPTKDM4EALDH1A1S1PR1NR1H4
SCHEMBL966219 0.82 KDM4E (0.52) MAPTKDM4EALDH1A1S1PR1NR1H4
SCHEMBL3080652 0.79 S1PR1 (0.53) MAPTKDM4EALDH1A1S1PR1NR1H4
SCHEMBL966738 0.79 MAPT (0.53) MAPTKDM4EALDH1A1NR1H4NPC1
SCHEMBL16436204 0.76 HSD17B10 (0.53) MAPTKDM4EALDH1A1NR1H4NPC1
SCHEMBL12948083 0.76 KDM4E (0.44) MAPTKDM4EALDH1A1S1PR1NR1H4
SCHEMBL16675215 0.75 HSD17B10 (0.49) MAPTKDM4EALDH1A1NR1H4NPC1
SCHEMBL1065563 0.75 KDM4E (0.52) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL12920442 0.75 KDM4E (0.46) MAPTKDM4EALDH1A1NR1H4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258804-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2012-08-22 EP disclosed
EP-2258804-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2010-12-08 EP disclosed
US-7795802-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2010-09-14 US disclosed
US-7365141-B2 Solvent resistance; luminescent film-forming solvent processible polymer which contains cross-linking so as to increase its molar mass and to resist solvent dissolution, the cross-linking being such that the polymer retains semiconductive and luminescent properties; capable of charge transport CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2008-04-29 US disclosed
EP-1801181-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2007-06-27 EP disclosed
EP-1715021-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
EP-1715020-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
US-7105621-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2006-09-12 US disclosed
US-20060151782-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2006-07-13 US disclosed
EP-1291406-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2006-06-21 EP disclosed
US-20050282983-A1 Crosslinking a luminescent film forming solvent processible polymer; solvent resistance; semiconductive polymers CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2005-12-22 US disclosed
US-6919415-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2005-07-19 US disclosed
EP-1006169-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2004-11-03 EP disclosed
US-6723811-B1 PHOTOLUMINESCENT AND ELECTROLUMINESCENT DEVICES; SEMICONDUCTOR POLYMER; ORGANIC LED; CROSSLINKING TO MAKE INSOLUBLE CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-04-20 US disclosed
US-20040059077-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-03-25 US disclosed
US-20030166810-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-09-04 US disclosed
US-6559256-B2 Luminescent film-forming solvent processible polymer for use in photoluminescent and electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-05-06 US disclosed
EP-1291406-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2003-03-12 EP disclosed
US-20030008991-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-01-09 US disclosed
EP-1006169-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2000-06-07 EP disclosed