Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | CASP1 | P29466 | 2/20 | 0.30 |
| ▸ | CASP7 | P55210 | 2/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640317 | 0.64 | CHRM3 (0.38) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL1812704 | 0.62 | CHRM3 (0.37) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL29279431 | 0.61 | TSHR (0.38) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5798986 | 0.58 | — | — | |
| SCHEMBL25250935 | 0.58 | CHRNB2 (0.33) | — | |
| SCHEMBL27678515 | 0.58 | CHRM3 (0.33) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL11596428 | 0.58 | — | — | |
| SCHEMBL11401168 | 0.57 | PTPN1 (0.40) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL10431184 | 0.57 | CHRM3 (0.50) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL5906945 | 0.57 | PTPN1 (0.50) | CHRM3LMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562001-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | Nura Bio, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026368-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. (US) | 2024-02-01 | — | — | WO | disclosed |