Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | MAOB | P27338 | 8/20 | 0.76 |
| ▸ | MAOA | P21397 | 7/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.75 |
| ▸ | BCHE | P06276 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807968 | 1.00 | MAPT (1.00) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL2807970 | 1.00 | MAPT (1.00) | MAPTMAOBMAOAMAPK1KMT2A | |
| Ethane SCHEMBL25195661 | 0.98 | MAPT (0.97) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL25195966 | 0.91 | MAOB (0.89) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL25233412 | 0.91 | MAOB (0.89) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL25219836 | 0.91 | MAOB (0.89) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL25191373 | 0.91 | MAOB (0.89) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL25208031 | 0.91 | MAPT (0.83) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL25199026 | 0.86 | MAPT (1.00) | MAPTMAOBMAOAMAPK1KMT2A | |
| SCHEMBL128913 | 0.86 | MAPT (1.00) | MAPTMAOBMAOAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624162-A | Flavonol derivative containing triazolopyridine and preparation method and application thereof | 贵州大学 | 2024-03-01 | — | — | CN | disclosed |