SCHEMBL2807968

SCHEMBL2807968

Cc1ccc(/C=C/C(=O)c2ccccc2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
MAOB P27338 8/20 0.76
MAOA P21397 7/20 0.76
MAPK1 P28482 3/20 0.76
KMT2A Q03164 3/20 0.76
MEN1 O00255 2/20 0.76
TDP1 Q9NUW8 2/20 0.76
KDM4E B2RXH2 2/20 0.76
ALDH1A1 P00352 2/20 0.76
CYP3A4 P08684 2/20 0.76
HPGD P15428 2/20 0.76
TP53 P04637 1/20 0.76
ALOX15 P16050 1/20 0.76
ALOX12 P18054 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
CYP2C19 P33261 2/20 0.75
BCHE P06276 1/20 0.75
CYP2D6 P10635 1/20 0.70
CYP2C9 P11712 1/20 0.70
CASP3 P42574 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30807207 1.00 MAPT (1.00) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL2807970 1.00 MAPT (1.00) MAPTMAOBMAOAMAPK1KMT2A
Ethane SCHEMBL25195661 0.98 MAPT (0.97) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL25195966 0.91 MAOB (0.89) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL25233412 0.91 MAOB (0.89) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL25219836 0.91 MAOB (0.89) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL25191373 0.91 MAOB (0.89) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL25208031 0.91 MAPT (0.83) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL25199026 0.86 MAPT (1.00) MAPTMAOBMAOAMAPK1KMT2A
SCHEMBL128913 0.86 MAPT (1.00) MAPTMAOBMAOAMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
CN-119954794-A Flavonol derivative containing benzothiazole, and preparation method and application thereof 贵州大学 2025-05-09 CN disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
CN-117510486-A Flavonol derivative containing thiadiazole, and preparation method and application thereof 贵州大学 2024-02-06 CN disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
WO-2022138482-A1 POLYMER-CONTAINING O/W-TYPE EMULSION COMPOSITION 住友精化株式会社 2022-06-30 WO disclosed
WO-2022138481-A1 POLYMER-CONTAINING O/W EMULSION COMPOSITION 住友精化株式会社 2022-06-30 WO disclosed
US-20100330018-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT L'OREAL (FR) 2010-12-30 US disclosed
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions L'OREAL (FR) 2010-06-10 US disclosed
WO-2007115181-A9 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEM CO (US) 2008-04-03 WO disclosed
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof EASTMAN CHEMICAL COMPANY 2007-11-01 US disclosed
WO-2007115181-A2 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEMICAL COMPANY (US) 2007-10-11 WO disclosed
EP-1525177-B1 SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES THEREOF GENFIT (FR) 2007-06-27 EP disclosed
US-4461907-A Amino-substituted flavans useful as anti-viral agents BURROUGHS WELLCOME CO. 1984-07-24 US disclosed
EP-0004579-B1 FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1982-08-18 EP disclosed
EP-0051061-A2 Novel intermediates and process for their preparation THE WELLCOME FOUNDATION LIMITED (GB) 1982-05-05 EP disclosed
EP-0004579-A1 Flavans, process for their preparation and pharmaceutical compositions containing them THE WELLCOME FOUNDATION LIMITED (GB) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof ABCC4, NCOA4, NR4A3 MAPT 4566/4885MAOB 1213/4885MAOA 1628/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAOB 1004/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885MAOA 3145/4885
US-20100330018-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT KRT18, FABP2, FABP4 MAPT 159/4885MAOB 1681/4885MAOA 762/4885
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions FASN, ALOX12, PAH MAPT 3479/4885MAOB 959/4885MAOA 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.