Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27153136 | 0.81 | MEN1 (0.40) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL12895235 | 0.78 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL8044895 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9095557 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL14786047 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL24795619 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9941474 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL20340796 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL8516755 | 0.77 | SMN1; SMN2 (0.90) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL19169564 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577211-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | Wake Forest University Health Sciences (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |