Phosphoric Acid

Phosphoric Acid

SCHEMBL308076

O.O.O.O.O=P([O-])(O)O.O=P([O-])(O)O.[Mn+2]

nearest known ligand 0.73

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.73
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 1/20 0.39
MMP2 P08253 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FDPS P14324 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 2/20 0.30
CA4 P22748 2/20 0.30
CA5A P35218 2/20 0.30
CA5B Q9Y2D0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL18421795 1.00 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL7608736 1.00 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL31501078 1.00 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL31381328 0.95 SLC34A1 (0.80) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL515615 0.95 SLC34A1 (0.80) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL1972676 0.90 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL210340 0.90 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL6851113 0.90 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL22770596 0.90 SLC34A1 (0.73) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL21906347 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093416-B2 Method for producing fatty acid alkyl esters and/or glycerin using fat or oil NIPPON SHOKUBAI CO., LTD. (JP) 2012-01-10 US disclosed
EP-0730672-B1 COMPOSITION AND PROCESS FOR TREATING MAGNESIUM-CONTAINING METALS AND PRODUCT THEREFROM HENKEL CORP (US) 2000-03-22 EP disclosed
US-5900074-A TREATMENT WITH A PH 2.0-5.0 AQUEOUS BATH THAT CONTAINS PHOSPHORIC ACID, MANGANESE ION, AND AMINE, THEREBY FORMING A CONVERSION COATING THAT CONTAINS P--MN AND MN--N AND/OR OTHER NITROGEN COMPOUNDS. HENKEL CORPORATION (US) 1999-05-04 US disclosed
US-5645650-A CONVERSION COATING HENKEL CORPORATION (US) 1997-07-08 US disclosed
EP-0730672-A1 COMPOSITION AND PROCESS FOR TREATING MAGNESIUM-CONTAINING METALS AND PRODUCT THEREFROM HENKEL CORPORATION (US) 1996-09-11 EP disclosed
EP-0730672-A4 COMPOSITION AND PROCESS FOR TREATING MAGNESIUM-CONTAINING METALS AND PRODUCT THEREFROM HENKEL CORP (US) 1996-07-09 EP disclosed
WO-1995012010-A1 COMPOSITION AND PROCESS FOR TREATING MAGNESIUM-CONTAINING METALS AND PRODUCT THEREFROM HENKEL CORPORATION (US) 1995-05-04 WO disclosed