Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21823066 | 0.78 | KDM4E (0.37) | MAPK1MAPTNPC1IRAK4KDM4E | |
| SCHEMBL28610278 | 0.76 | AR (0.38) | MAPK1MAPTNPC1IRAK4CYP2C9 | |
| SCHEMBL21823070 | 0.76 | IRAK4 (0.38) | MAPK1MAPTPOLBNPC1IRAK4 | |
| SCHEMBL29606803 | 0.76 | NPC1 (0.60) | MAPK1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL17602643 | 0.76 | NPC1 (0.60) | MAPK1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL30748842 | 0.74 | LRRK2 (0.47) | MAPTPOLBNPC1RAB9AKDM4E | |
| SCHEMBL30808040 | 0.70 | NPC1 (0.47) | MAPK1LPAR2MAPTNPC1ALDH1A1 | |
| SCHEMBL19933208 | 0.70 | NPC1 (0.47) | MAPK1LPAR2MAPTNPC1ALDH1A1 | |
| SCHEMBL27953637 | 0.69 | PIK3CA (0.38) | MAPK1MAPTPOLBIRAK4KDM4E | |
| SCHEMBL5031567 | 0.67 | KDM4E (0.47) | MAPK1MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |