Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748740 | 0.85 | LRRK2 (0.50) | LRRK2PTK2INSRALKFGFR3 | |
| SCHEMBL30749101 | 0.82 | LRRK2 (0.44) | LRRK2PTK2INSRALKMAPT | |
| SCHEMBL30748957 | 0.78 | LRRK2 (0.41) | LRRK2PTK2INSRALKFGFR3 | |
| SCHEMBL30808288 | 0.74 | MAPK1 (0.39) | MAPTALDH1A1KDM4EHTTPKM | |
| SCHEMBL30748864 | 0.70 | LRRK2 (0.51) | LRRK2PTK2INSRALKFGFR3 | |
| SCHEMBL24590200 | 0.68 | LRRK2 (0.61) | LRRK2PTK2INSRALKMAPT | |
| SCHEMBL14137147 | 0.68 | MAPT (0.52) | PTK2MAPTALDH1A1KDM4EHTT | |
| SCHEMBL30748749 | 0.67 | HTR2C (0.43) | LRRK2PTK2MAPTALDH1A1KDM4E | |
| SCHEMBL30080932 | 0.66 | TTK (0.58) | INSRALKMAPTALDH1A1KDM4E | |
| SCHEMBL2917121 | 0.66 | DHFR (0.56) | LRRK2INSRALKCHEK1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |