Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21823085 | 1.00 | MAPK1 (0.42) | MAPK1GPR35GPR119NPC1PKM | |
| SCHEMBL21823045 | 0.78 | MAPK1 (0.63) | MAPK1NPC1PKM | |
| SCHEMBL21823036 | 0.76 | MAPK1 (0.47) | MAPK1GPR119NPC1PKM | |
| SCHEMBL30808297 | 0.76 | MAPK1 (0.47) | MAPK1GPR119NPC1PKM | |
| SCHEMBL441195 | 0.73 | AXL (0.37) | GPR35GPR119PIP4K2C | |
| SCHEMBL30808244 | 0.73 | AXL (0.37) | GPR35GPR119PIP4K2C | |
| SCHEMBL438091 | 0.73 | GPR35 (0.37) | GPR35GPR119NPC1PKMPIP4K2C | |
| SCHEMBL21822980 | 0.73 | GPR35 (0.37) | GPR35GPR119NPC1PKMPIP4K2C | |
| SCHEMBL30808281 | 0.71 | PIP4K2C (0.42) | GPR35GPR119PIP4K2C | |
| SCHEMBL28606328 | 0.71 | PIP4K2C (0.42) | GPR35GPR119PIP4K2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |