Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511510 | 0.91 | ALDH1A1 (0.56) | ALDH1A1PKMMEN1GSK3AGSK3B | |
| SCHEMBL30808658 | 0.87 | ALDH1A1 (0.46) | ALDH1A1PKMMEN1KMT2AFPR2 | |
| SCHEMBL10648891 | 0.84 | TSHR (0.48) | ALDH1A1MEN1GSK3AGSK3BKMT2A | |
| SCHEMBL4328088 | 0.81 | NPY5R (0.51) | MEN1GSK3AGSK3BKMT2ANPSR1 | |
| SCHEMBL10511901 | 0.79 | KCNN4 (0.46) | ALDH1A1PKMMEN1GSK3AGSK3B | |
| SCHEMBL29456205 | 0.78 | NOTUM (0.50) | ALDH1A1MEN1KMT2AFPR2TP53 | |
| SCHEMBL3782479 | 0.78 | NOTUM (0.50) | ALDH1A1MEN1KMT2AFPR2TP53 | |
| SCHEMBL30808603 | 0.78 | MEN1 (0.50) | ALDH1A1MEN1GSK3AGSK3BKMT2A | |
| SCHEMBL4971618 | 0.77 | NPSR1 (0.67) | ALDH1A1MEN1GSK3AGSK3BKMT2A | |
| SCHEMBL30808619 | 0.77 | NPSR1 (0.67) | ALDH1A1MEN1GSK3AGSK3BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250002-A1 | IDENTIFICATION OF NOVEL BENZOTHIAZONES AS TAU-SH3 INTERACTION INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | SOUTHERN RESEARCH INSTITUTE (US) | 2023-12-28 | — | — | WO | disclosed |