Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072348 | 0.90 | PYGM (0.57) | PYGMSMN1; SMN2TSHRLMNAMAPT | |
| SCHEMBL766623 | 0.77 | PYGM (0.45) | PYGMSMN1; SMN2TSHRLMNAMAPT | |
| SCHEMBL3066357 | 0.76 | SMN1; SMN2 (0.45) | PYGMSMN1; SMN2TSHRLMNAPMP22 | |
| SCHEMBL3071099 | 0.76 | PYGM (0.55) | PYGMP2RY6P2RY2P2RY4TK2 | |
| SCHEMBL3083986 | 0.76 | PYGM (0.39) | PYGMSMN1; SMN2TSHRLMNAMAPT | |
| SCHEMBL3968336 | 0.76 | PYGM (0.54) | PYGMSMN1; SMN2TSHRLMNAMAPT | |
| SCHEMBL3978675 | 0.76 | PYGM (0.54) | PYGMSMN1; SMN2TSHRLMNAMAPT | |
| SCHEMBL368853 | 0.75 | PYGM (0.77) | PYGMP2RY6P2RY2P2RY4TK2 | |
| SCHEMBL4601745 | 0.75 | PYGM (0.77) | PYGMP2RY6P2RY2P2RY4TK2 | |
| SCHEMBL12642313 | 0.75 | PYGM (0.77) | PYGMP2RY6P2RY2P2RY4TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054406-B1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | RESPROTECT GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-8492537-B2 | Nucleosides for suppressing or reducing the development of resistance in cytostatic therapy | RESPROTECT GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20100227834-A1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | RESprotech GmbH (DE) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227834-A1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | TYMP, ENTPD5, NTPCR | PYGM 1888/4885SMN1; SMN2 1379/4885TSHR 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.