Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770713 | 0.79 | LMNA (0.42) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2625503 | 0.79 | LMNA (0.42) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31492955 | 0.76 | LMNA (0.40) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL26685839 | 0.76 | LMNA (0.40) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL26685323 | 0.76 | LMNA (0.40) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30632665 | 0.76 | LMNA (0.40) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1670844 | 0.74 | LMNA (0.41) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30755868 | 0.70 | LMNA (0.36) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31543569 | 0.69 | CCR4 (0.31) | HSD17B10 | |
| SCHEMBL31492981 | 0.68 | LMNA (0.37) | LMNAHTTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543544-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119866338-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| WO-2023250064-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-12-28 | — | — | WO | disclosed |