Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13732358 | 0.86 | XIAP (0.48) | NOTUMKDM1AXIAPBIRC2NR1H2 | |
| SCHEMBL26863452 | 0.83 | NOTUM (0.36) | NOTUMKDM1ANR1H2SCD5 | |
| SCHEMBL30808966 | 0.82 | UCHL1 (0.39) | NOTUMKDM1ANR1H2HDAC1HDAC6 | |
| SCHEMBL17436484 | 0.82 | NOTUM (0.58) | NOTUMXIAPBIRC2CYP11B2 | |
| SCHEMBL17807352 | 0.78 | KDM1A (0.43) | NOTUMKDM1ANR1H2CYP11B2 | |
| SCHEMBL31492094 | 0.76 | XIAP (0.49) | NOTUMKDM1AXIAPBIRC2NR1H2 | |
| SCHEMBL16441383 | 0.76 | XIAP (0.49) | NOTUMKDM1AXIAPBIRC2NR1H2 | |
| SCHEMBL13732290 | 0.75 | XIAP (0.45) | KDM1AXIAPBIRC2HDAC1HDAC6 | |
| SCHEMBL17252097 | 0.75 | NR1H2 (0.49) | NOTUMKDM1AXIAPBIRC2NR1H2 | |
| SCHEMBL17807330 | 0.74 | NOTUM (0.64) | NOTUMKDM1AHDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543544-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119866338-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| WO-2023250064-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-12-28 | — | — | WO | disclosed |