Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145053 | 1.00 | ADORA2A (0.41) | ADORA2AADORA2BTPMTMEN1LMNA | |
| SCHEMBL4402971 | 0.86 | ADORA2A (0.41) | ADORA2AADORA2BMEN1LMNAKMT2A | |
| SCHEMBL25367875 | 0.85 | ADORA2A (0.41) | ADORA2AADORA2BTPMTMEN1LMNA | |
| SCHEMBL1145133 | 0.85 | TTR (0.43) | ADORA2AADORA2BTPMTMEN1LMNA | |
| SCHEMBL1144961 | 0.83 | MEN1 (0.39) | ADORA2AADORA2BTPMTMEN1LMNA | |
| SCHEMBL1144382 | 0.83 | MAPK1 (0.39) | TPMTDAOHCAR2TTRMAPK1 | |
| SCHEMBL1144821 | 0.82 | CNR2 (0.49) | TPMTLMNAKMT2ATTRMAPK1 | |
| SCHEMBL4402977 | 0.81 | ADORA2A (0.38) | ADORA2AADORA2BMEN1LMNAKMT2A | |
| SCHEMBL4140051 | 0.81 | ADORA2A (0.38) | ADORA2AADORA2BLMNA | |
| SCHEMBL31637404 | 0.79 | TSHR (0.44) | LMNATTRALPLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562017-A1 | NOVEL ACC INHIBITORS | Pfizer Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120019059-A | Novel ACC inhibitors | 辉瑞公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-118984827-A | GLP-1R modulating compounds | 歌礼生物科技（杭州）有限公司 | 2024-11-19 | — | — | CN | disclosed |
| WO-2024023727-A1 | NOVEL ACC INHIBITORS | PFIZER INC. (US) | 2024-02-01 | — | — | WO | disclosed |