Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.43 |
| ▸ | JAK2 | O60674 | 11/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018373 | 0.85 | JAK1 (0.44) | JAK1JAK2TYK2 | |
| SCHEMBL28932573 | 0.85 | JAK1 (0.44) | JAK1JAK2TYK2 | |
| SCHEMBL23668193 | 0.85 | JAK1 (0.43) | JAK1JAK2TYK2 | |
| SCHEMBL30810116 | 0.83 | JAK1 (0.44) | JAK1JAK2 | |
| SCHEMBL30810113 | 0.82 | JAK2 (0.34) | JAK1JAK2TYK2 | |
| SCHEMBL30350089 | 0.79 | JAK2 (0.46) | JAK1JAK2 | |
| SCHEMBL28997571 | 0.79 | JAK2 (0.46) | JAK1JAK2 | |
| SCHEMBL21870794 | 0.77 | JAK1 (0.61) | JAK1JAK2TYK2 | |
| SCHEMBL31218203 | 0.74 | JAK1 (0.47) | JAK1JAK2TYK2 | |
| SCHEMBL28932572 | 0.72 | JAK1 (0.44) | JAK1JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112823159-B | Aromatic heterocyclic compounds with kinase inhibitory activity | 上海轶诺药业有限公司 | 2024-03-01 | — | — | CN | disclosed |