Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30810272 | 0.89 | KDM4E (0.41) | KDM4EGCKHSD17B10ACLYAPLNR | |
| SCHEMBL19612159 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2TSHRSERPINH1 | |
| SCHEMBL30810455 | 0.80 | TDP1 (0.39) | KDM4EALDH1A1SMN1; SMN2TSHRGCK | |
| SCHEMBL30810337 | 0.78 | CFTR (0.51) | KDM4EALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL13279910 | 0.75 | HCRTR1 (0.39) | KDM4EALDH1A1SMN1; SMN2TSHRHCRTR1 | |
| SCHEMBL13280393 | 0.73 | EZH2 (0.41) | KDM4EALDH1A1HCRTR1HCRTR2HPGD | |
| SCHEMBL19612152 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL29964430 | 0.72 | OPRK1 (0.42) | ALDH1A1SMN1; SMN2TSHRGCKHSD17B10 | |
| SCHEMBL29964499 | 0.72 | GAA (0.46) | KDM4EALDH1A1SMN1; SMN2TSHRGCK | |
| SCHEMBL13280007 | 0.71 | EZH2 (0.54) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |