SCHEMBL30811409

SCHEMBL30811409

Nc1ccn(CCCF)c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30811415 0.80
SCHEMBL31510735 0.63 NPC1 (0.40) CA12CA1CA2CA9
SCHEMBL14499206 0.62 HTR2A (0.35) CA12CA1CA2CA9
SCHEMBL16943123 0.61 MAPT (0.46)
SCHEMBL28293477 0.61
SCHEMBL1662883 0.59
SCHEMBL536196 0.58 TP53 (0.39)
SCHEMBL12690555 0.57 HTR1D (0.35)
SCHEMBL536215 0.56 TP53 (0.37)
SCHEMBL17128963 0.56 DOHH (0.50) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813288-A Arylamino derivative estrogen receptor modulator and use thereof 西藏海思科制药有限公司 2024-04-02 CN disclosed