Chrysophanol

Chrysophanol

SCHEMBL308131

Cc1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
MAPT P10636 5/20 1.00
TSHR P16473 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
ELANE P08246 4/20 1.00
MAPK1 P28482 3/20 1.00
CYP3A4 P08684 3/20 1.00
KDM4E B2RXH2 3/20 1.00
RECQL P46063 2/20 1.00
USP2 O75604 1/20 1.00
BRCA1 P38398 1/20 1.00
MAOA P21397 4/20 0.69
ALOX15 P16050 4/20 0.69
LMNA P02545 3/20 0.69
MAOB P27338 3/20 0.69
HSD17B10 Q99714 3/20 0.69
HPGD P15428 3/20 0.69
SMN1; SMN2 Q16637 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chrysophanol SCHEMBL8674524 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTSHRTDP1MEN1
Chrysophanol SCHEMBL30457995 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTSHRTDP1MEN1
Chrysophanol SCHEMBL29730935 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTSHRTDP1MEN1
Chrysophanol SCHEMBL29364442 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTSHRTDP1MEN1
Chrysophanol SCHEMBL9879838 0.97 ALDH1A1 (0.94) ALDH1A1MAPTTSHRTDP1MEN1
Chrysophanol SCHEMBL3272393 0.95 ALDH1A1 (0.91) ALDH1A1MAPTTSHRTDP1MEN1
SCHEMBL19461856 0.95 ALDH1A1 (0.90) ALDH1A1MAPTTSHRTDP1MEN1
Physcion SCHEMBL5015452 0.89 ELANE (0.81) ALDH1A1MAPTTSHRTDP1MEN1
Chrysophanol SCHEMBL2687351 0.89 ALDH1A1 (0.78) ALDH1A1MAPTTSHRTDP1MEN1
SCHEMBL12304029 0.87 ELANE (0.85) ALDH1A1MAPTTSHRTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8081 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031318-A Natural Chinese herbal medicine hair-nourishing composition and preparation process thereof 家人(佛山市)企业管理有限公司 2026-05-15 CN claimed
US-20260110969-A1 COMPOSITION FOR REMOVING EDGE BEADS FROM METAL-CONTAINING RESISTS, DEVELOPER COMPOSITION OF METAL-CONTAINING RESISTS, AND METHOD OF FORMING PATTERNS USING THE COMPOSITION SAMSUNG SDI CO LTD (KR) 2026-04-23 US claimed
CN-116577448-B Quality control method of magnolia bark and seven-material soup 华南农业大学 2026-02-27 CN claimed
CN-121583384-A Nucleic acid-small molecule non-covalent complex and preparation method and application thereof 上海中医药大学 2026-02-27 CN claimed
CN-121574836-A Chaetomium globosum, method for separating secondary metabolites thereof and application 广东药科大学 2026-02-27 CN claimed
EP-4698175-A1 LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-02-25 EP claimed
EP-3639854-B1 MTOR-INHIBITOR-CONTAINING MEDICINE FOR TREATING OR PREVENTING FUCHS' ENDOTHELIAL CORNEAL DYSTROPHY THE DOSHISHA (JP) 2026-01-07 EP claimed
US-12509729-B2 Compositions and methods for the diagnosis and treatment of lymphatic system disorders THE CHILDREN'S HOSPTAL OF PHILADELPHIA (US) 2025-12-30 US claimed
EP-4635293-A2 PRODUCTION OF COLOURED FUNGAL MYCELIUM Mushlabs GmbH (DE) 2025-10-22 EP claimed
EP-4629989-A2 TREATMENT OR PREVENTION OF DEPRESSIVE DISORDERS THROUGH COMBINATION THERAPY Freedom Biosciences, Inc. (US) 2025-10-15 EP claimed
CN-1128162-A Preparation of granula for tonifying kidney and hairs WANG YONGQING (CN) 1996-08-07 CN claimed
EP-0496349-B1 Coating solution for preventing adhesion of polymer scale and method for its use SHINETSU CHEMICAL CO (JP) 1996-04-10 EP claimed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed
CN-1076368-A Compound glossy ganoderma nutrient solution and preparation method thereof LI RUQING (CN) 1993-09-22 CN claimed
US-5241022-A Polyvinyl alcohol with saponification of not less than seventy percent and quinone SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-31 US claimed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO claimed