Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 11/20 | 0.53 |
| ▸ | ABL1 | P00519 | 6/20 | 0.52 |
| ▸ | EGFR | P00533 | 6/20 | 0.52 |
| ▸ | ABL2 | P42684 | 6/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | SIK1 | P57059 | 1/20 | 0.47 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.47 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217772 | 1.00 | SRC (0.57) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL27217867 | 0.96 | SRC (0.58) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL30813394 | 0.96 | SRC (0.58) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL27217872 | 0.85 | SRC (0.55) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL30813428 | 0.85 | SRC (0.55) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL30813461 | 0.82 | RIPK2 (0.56) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL27217819 | 0.82 | RIPK2 (0.56) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL30813404 | 0.81 | IGF1R (0.47) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL27217870 | 0.81 | IGF1R (0.47) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL30813564 | 0.79 | SRC (0.41) | SRCRIPK2ABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |