Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 10/20 | 0.47 |
| ▸ | SRC | P12931 | 10/20 | 0.47 |
| ▸ | INSR | P06213 | 6/20 | 0.47 |
| ▸ | LYN | P07948 | 4/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.47 |
| ▸ | LATS1 | O95835 | 1/20 | 0.47 |
| ▸ | YES1 | P07947 | 1/20 | 0.47 |
| ▸ | HCK | P08631 | 1/20 | 0.47 |
| ▸ | FECH | P22830 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.47 |
| ▸ | STK4 | Q13043 | 1/20 | 0.47 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30813404 | 1.00 | IGF1R (0.47) | IGF1RSRCINSRLYNROCK2 | |
| SCHEMBL30813473 | 0.84 | SRC (0.41) | IGF1RSRCEGFR | |
| SCHEMBL27217862 | 0.82 | SRC (0.40) | IGF1RSRCEGFR | |
| SCHEMBL8930711 | 0.82 | EGFR (0.67) | IGF1RSRCINSRLYNROCK2 | |
| SCHEMBL27217863 | 0.81 | SRC (0.40) | IGF1RSRCEGFR | |
| SCHEMBL27217772 | 0.81 | SRC (0.57) | SRCRETRIPK2RIPK3EGFR | |
| SCHEMBL30813385 | 0.81 | SRC (0.57) | SRCRETRIPK2RIPK3EGFR | |
| SCHEMBL30813394 | 0.79 | SRC (0.58) | IGF1RSRCINSRLYNRET | |
| SCHEMBL27217867 | 0.79 | SRC (0.58) | IGF1RSRCINSRLYNRET | |
| SCHEMBL23966762 | 0.79 | RIPK2 (0.62) | IGF1RSRCINSRLYNROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-05-16 | — | — | US | disclosed |
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | IGF1R 4350/4885SRC 1597/4885INSR 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.