Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 6/20 | 0.32 |
| ▸ | EGFR | P00533 | 4/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | ABL2 | P42684 | 2/20 | 0.30 |
| ▸ | CDK1 | P06493 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217697 | 0.96 | SRC (0.33) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL30813416 | 0.91 | SRC (0.32) | SRCEGFRKDR | |
| SCHEMBL27217800 | 0.87 | SRC (0.32) | SRCEGFRKDRABL1ABL2 | |
| SCHEMBL27217699 | 0.83 | RAB9A (0.32) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL30813527 | 0.82 | KDR (0.37) | PI4KBSRCEGFRKDRPIK3CD | |
| SCHEMBL30813586 | 0.81 | RET (0.35) | SRCNEK7 | |
| SCHEMBL30813564 | 0.81 | SRC (0.41) | SRCEGFRKDRABL1ABL2 | |
| SCHEMBL30813431 | 0.81 | SRC (0.36) | SRC | |
| SCHEMBL30813443 | 0.80 | FLT3 (0.38) | — | |
| SCHEMBL30813458 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-05-16 | — | — | US | disclosed |
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | PI4KA 658/4885PI4K2B 752/4885PI4K2A 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.