Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088052 | 0.99 | NR1H2 (0.58) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL22559392 | 0.85 | ALDH1A1 (0.46) | NR1H2ALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL23326756 | 0.84 | NR1H2 (0.39) | NR1H2ALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL27088102 | 0.84 | KCNJ1 (0.41) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL22559469 | 0.82 | NR1H2 (0.37) | NR1H2ALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL24192765 | 0.79 | NR1H2 (0.74) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL29959234 | 0.79 | NR1H2 (0.74) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL24565974 | 0.77 | NR1H2 (0.61) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL24192763 | 0.76 | NR1H2 (0.70) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL15688199 | 0.75 | NR1H2 (0.80) | NR1H2ALDH1A1KDM4EATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |