SCHEMBL3081379

SCHEMBL3081379

CCC(=O)OCc1ccccc1NC(=O)OCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.66
NPC1 O15118 3/20 0.66
ALDH1A1 P00352 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MAPT P10636 2/20 0.49
CASP3 P42574 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.48
MAPK1 P28482 1/20 0.46
MAOB P27338 1/20 0.46
MGLL Q99685 1/20 0.46
PLAU P00749 1/20 0.46
PTPN1 P18031 1/20 0.46
KMT2A Q03164 2/20 0.45
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
ATM Q13315 1/20 0.44
GAA P10253 1/20 0.44
ENPP2 Q13822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9588889 0.87 NPC1 (0.70) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL15516309 0.81 NPC1 (0.66) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL111605 0.81 ALDH1A1 (0.68) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL1871761 0.81 ALDH1A1 (0.68) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL1163050 0.80 NPC1 (0.64) RAB9ANPC1ALDH1A1MAPTCASP3
SCHEMBL4291027 0.80 NPC1 (0.64) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL3083502 0.80 NPC1 (0.60) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL5853278 0.80 NPC1 (1.00) RAB9ANPC1ALDH1A1L3MBTL1MAPT
Hydrochloric Acid SCHEMBL27438937 0.79 ALDH1A1 (0.66) RAB9ANPC1ALDH1A1L3MBTL1MAPT
SCHEMBL27168266 0.79 ALDH1A1 (0.66) RAB9ANPC1ALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795166-B2 Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method N.E. CHEMCAT CORPORATION (JP) 2010-09-14 US disclosed
US-20070155617-A1 FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD N. E. CHEMCAT CORPORATION (JP) 2007-07-05 US disclosed