Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30814749 | 0.93 | MAPT (0.37) | MAPTPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL23042411 | 0.85 | MAPT (0.39) | MAPTPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29612473 | 0.85 | MAPT (0.39) | MAPTPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL25877480 | 0.80 | MAPT (0.38) | MAPTPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL12028784 | 0.73 | MAPK1 (0.44) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29612465 | 0.72 | MAPK1 (0.36) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28730678 | 0.72 | MAPK1 (0.36) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29612887 | 0.71 | MAPK1 (0.35) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23042586 | 0.71 | MAPK1 (0.35) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29612526 | 0.71 | MAPK1 (0.40) | MAPTALDH1A1KDM4EMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046221-A1 | EGFR INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-03-07 | — | — | WO | disclosed |