Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GRK6 | P43250 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28730679 | 1.00 | MAPK1 (0.40) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL29612473 | 0.78 | MAPT (0.39) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL23042411 | 0.78 | MAPT (0.39) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL28730678 | 0.76 | MAPK1 (0.36) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL25877480 | 0.76 | MAPT (0.38) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL29612465 | 0.76 | MAPK1 (0.36) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL23042586 | 0.75 | MAPK1 (0.35) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL29612887 | 0.75 | MAPK1 (0.35) | MAPK1PKMRAB9AKDM4EMAPT | |
| SCHEMBL1515031 | 0.74 | ALDH1A1 (0.57) | RAB9AMAPTALDH1A1KAT2B | |
| SCHEMBL29612519 | 0.74 | ALDH1A1 (0.57) | RAB9AMAPTALDH1A1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |