SCHEMBL3081479

SCHEMBL3081479

COc1cncnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4354057 0.78 AOC3 (0.47)
Sulfanilamide SCHEMBL27962185 0.77 CA2 (0.46)
SCHEMBL10033203 0.74
SCHEMBL18838245 0.74 CYP17A1 (0.42)
SCHEMBL907670 0.74 KDM4E (0.43)
SCHEMBL24729703 0.73
SCHEMBL8983616 0.73
SCHEMBL29919731 0.73
SCHEMBL25401159 0.73
SCHEMBL1359723 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362335-B1 None US claimed
CN-118812441-A Industrial sulfanilamide production and preparation process 安达裕顺化工有限公司 2024-10-22 CN claimed
CN-114948993-A Preparation method and application of skin gel for treating tinea capitis, skin eczema and acne 罗露曦 2022-08-30 CN claimed
EP-1289994-B1 PROCESS FOR THE PREPARATION OF 2-AMINO-5,8-DIMETHOXY 1,2,4]TRIAZOLO 1,5-c]PYRIMIDINE DOW AGROSCIENCES LLC (US) 2004-03-17 EP claimed
EP-1289994-A1 PROCESS FOR THE PREPARATION OF 2-AMINO-5,8-DIMETHOXY 1,2,4]TRIAZOLO 1,5-c]PYRIMIDINE Dow AgroSciences LLC (US) 2003-03-12 EP claimed
US-6362335-B2 CONTACTING 3-AMINO-8-METHOXY(1,2,4) TRIAZOLO(4,3-C)PYRIMIDINE COMPOUNDS WITH SODIUM OR POTASSIUM METHOXIDE IN AN ALCOHOL SOLVENT DOW AGROSCIENCES LLC 2002-03-26 US claimed
US-20020013230-A1 Process for the preparation of 2-amino-5, 8-dimethoxy (1,2,4) triazolo (1,5-c) pyrimidine CORTEVA AGRISCIENCE LLC 2002-01-31 US claimed
WO-2001098305-A1 PROCESS FOR THE PREPARATION OF 2-AMINO-5,8-DIMETHOXY[1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DOW AGROSCIENCES LLC (US) 2001-12-27 WO claimed
US-6362335-B1 None US disclosed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-20260108527-A1 POLO LIKE KINASE 4 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2026-04-23 US disclosed
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2026-03-26 US disclosed
US-12570631-B2 Substituted N-(4-(pyrimidin and pyridin-4-yl)benzylcarboxamides and its use for treating disorders responsive to inhibition of Btk BIOGEN MA INC. (US) 2026-03-10 US disclosed
CN-120987854-A Preparation process of industrial sulfanilamide 内蒙古博霖制药有限公司 2025-11-21 CN disclosed
CN-1085556-A The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine BRISTOL MYERS SQUIBB CO (US) 1994-04-20 CN disclosed
US-5300506-A Indole-3-alkyl derivatives of alkoxypyrimidinylpiperazines BRISTOL-MYERS SQUIBB COMPANY (US) 1994-04-05 US disclosed
EP-0548813-A1 Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines Bristol-Myers Squibb Company (US) 1993-06-30 EP disclosed
EP-0464604-A2 1-Indolylalkyl-4-(alkoxy-pyrimidinyl)piperazines Bristol-Myers Squibb Company (US) 1992-01-08 EP disclosed
EP-0464558-A1 Antimigraine alkoxypyrimidine derivatives Bristol-Myers Squibb Company (US) 1992-01-08 EP disclosed
US-5077293-A Antidepressants BRISTOL-MYERS SQUIBB CO. (US) 1991-12-31 US disclosed