⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928780 | 0.88 | — | — | |
| SCHEMBL130166 | 0.85 | — | — | |
| SCHEMBL14549983 | 0.76 | KDM4E (0.41) | — | |
| SCHEMBL22041818 | 0.75 | — | — | |
| SCHEMBL2230245 | 0.75 | — | — | |
| SCHEMBL29896316 | 0.75 | — | — | |
| SCHEMBL29461641 | 0.75 | — | — | |
| SCHEMBL6585133 | 0.75 | THRB (0.42) | — | |
| SCHEMBL14549984 | 0.75 | KDM4E (0.40) | — | |
| SCHEMBL14549985 | 0.73 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594318-A1 | AKT1 MODULATORS | Alterome Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |