Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227241 | 1.00 | MAPT (0.41) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27226907 | 0.84 | MAPT (0.42) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27227041 | 0.81 | MAPT (0.42) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27227145 | 0.81 | MAPT (0.54) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27226191 | 0.81 | MAPT (0.41) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27226838 | 0.81 | MEN1 (0.51) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL30815301 | 0.81 | MEN1 (0.51) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27227025 | 0.80 | TXNRD1 (0.46) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL30815817 | 0.78 | PTK2 (0.43) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL30814928 | 0.78 | MAPT (0.45) | MAPTKMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594318-A1 | AKT1 MODULATORS | Alterome Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |