Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28465582 | 1.00 | S1PR1 (0.52) | S1PR1S1PR3S1PR5PLA2G4BPPARD | |
| SCHEMBL23117708 | 1.00 | S1PR1 (0.52) | S1PR1S1PR3S1PR5PLA2G4BPPARD | |
| SCHEMBL22829357 | 0.83 | LTA4H (0.43) | S1PR1S1PR3LTA4HGAAL3MBTL1 | |
| SCHEMBL22829398 | 0.83 | LTA4H (0.43) | S1PR1S1PR3LTA4HGAAL3MBTL1 | |
| SCHEMBL21295990 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 | |
| SCHEMBL30815917 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 | |
| SCHEMBL21308980 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 | |
| SCHEMBL30816215 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 | |
| SCHEMBL21296003 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 | |
| SCHEMBL21297037 | 0.74 | S1PR5 (0.38) | S1PR1S1PR3S1PR5HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757869-B | Compounds having S1P5 receptor agonistic activity | 小野药品工业株式会社 | 2024-03-08 | — | — | CN | disclosed |