Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165624 | 0.79 | MAPT (0.63) | MAPTLMNAHTTNPC1POLB | |
| SCHEMBL17100630 | 0.76 | SMN1; SMN2 (0.59) | MAPTLMNAHTTNPC1POLB | |
| SCHEMBL17115031 | 0.75 | MAPT (0.58) | MAPTLMNAHTTNPC1NPSR1 | |
| SCHEMBL30584898 | 0.74 | MAPT (0.64) | MAPTLMNAHTTNPC1POLB | |
| SCHEMBL30816313 | 0.74 | MAPT (0.64) | MAPTLMNAHTTNPC1ALDH1A1 | |
| SCHEMBL27979662 | 0.74 | POLB (0.84) | MAPTLMNAHTTPOLBALDH1A1 | |
| SCHEMBL18624608 | 0.74 | MAPT (0.62) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL5060999 | 0.73 | SMN1; SMN2 (0.77) | MAPTLMNAPOLBALDH1A1HPGD | |
| SCHEMBL31546316 | 0.72 | MAPT (0.76) | MAPTLMNAHTTNPC1POLB | |
| SCHEMBL31546320 | 0.72 | MAPT (0.75) | MAPTLMNAHTTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117503772-A | Compound for inhibiting hepatitis B surface antigen and application thereof | 重庆医科大学国际体外诊断研究院 | 2024-02-06 | — | — | CN | disclosed |