Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165586 | 0.82 | MAPT (0.62) | MAPTGAATHRBHTTLMNA | |
| SCHEMBL29165624 | 0.80 | MAPT (0.63) | MAPTTHRBHTTLMNAALDH1A1 | |
| SCHEMBL29165633 | 0.78 | MAPT (0.65) | MAPTTHRBHTTLMNAALDH1A1 | |
| SCHEMBL20116598 | 0.75 | MAPT (0.55) | MAPTGAATHRBHTTLMNA | |
| SCHEMBL20116596 | 0.75 | MAPT (0.60) | MAPTGAATHRBHTTLMNA | |
| SCHEMBL30816312 | 0.74 | MAPT (0.57) | MAPTHTTLMNAALDH1A1NPC1 | |
| SCHEMBL17115031 | 0.73 | MAPT (0.58) | MAPTGAATHRBHTTLMNA | |
| SCHEMBL30584898 | 0.72 | MAPT (0.64) | MAPTGAATHRBHTTLMNA | |
| SCHEMBL17100634 | 0.72 | MAPT (0.65) | MAPTGAATHRBLMNAALDH1A1 | |
| SCHEMBL7076852 | 0.72 | MAPT (0.54) | MAPTGAATHRBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117503772-A | Compound for inhibiting hepatitis B surface antigen and application thereof | 重庆医科大学国际体外诊断研究院 | 2024-02-06 | — | — | CN | disclosed |