SCHEMBL30816403

SCHEMBL30816403

Cc1cc(C(C)(C)c2ccc(OC[C@@H](O)CCl)c(C)c2)ccc1OC[C@H](O)CO

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 12/20 0.67
VDR P11473 10/20 0.62
KDM4E B2RXH2 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19460228 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL19459647 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL30816338 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL19483474 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL19459816 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL30816341 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL30816371 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL19459687 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL19459648 1.00 AR (0.67) ARVDRKDM4ECYP1A2
SCHEMBL16688238 0.94 AR (0.79) ARVDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250100986-A1 BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-03-27 US disclosed
US-11919874-B2 Bisphenol derivatives and their use as androgen receptor activity modulators THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250100986-A1 BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS AR, SHBG, NR5A1 AR 1/4885VDR 28/4885KDM4E 2560/4885
US-11919874-B2 Bisphenol derivatives and their use as androgen receptor activity modulators AR, SHBG, NR5A1 AR 1/4885VDR 28/4885KDM4E 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.