Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.61 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281553 | 1.00 | CRBN (0.61) | CRBNCSNK1A1 | |
| SCHEMBL31158857 | 0.92 | CRBN (0.61) | CRBNCSNK1A1 | |
| SCHEMBL25802989 | 0.83 | CRBN (0.71) | CRBNCSNK1A1 | |
| SCHEMBL27122120 | 0.83 | CRBN (0.61) | CRBN | |
| SCHEMBL29892045 | 0.83 | CRBN (0.61) | CRBN | |
| SCHEMBL30042984 | 0.82 | CRBN (0.72) | CRBNCSNK1A1 | |
| SCHEMBL17697800 | 0.81 | CRBN (0.71) | CRBNCSNK1A1 | |
| SCHEMBL24192574 | 0.80 | CRBN (0.69) | CRBNCSNK1A1 | |
| SCHEMBL1413692 | 0.79 | CRBN (0.62) | CRBNCSNK1A1 | |
| SCHEMBL4448246 | 0.79 | CRBN (0.59) | CRBNCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917410-A | Pan-KRAS degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |