Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.61 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.51 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816875 | 0.92 | CRBN (0.61) | CRBNCSNK1A1 | |
| SCHEMBL29281553 | 0.92 | CRBN (0.61) | CRBNCSNK1A1 | |
| SCHEMBL31731537 | 0.87 | CRBN (0.61) | CRBNCSNK1A1IKZF2GSPT1CYP2C19 | |
| SCHEMBL31135343 | 0.83 | CRBN (0.71) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL29892045 | 0.83 | CRBN (0.61) | CRBNIKZF2DDB1 | |
| SCHEMBL27122120 | 0.83 | CRBN (0.61) | CRBNIKZF2DDB1 | |
| SCHEMBL20154001 | 0.82 | CRBN (0.72) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL22713505 | 0.82 | CRBN (0.63) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL31403699 | 0.81 | CRBN (0.71) | CRBNCSNK1A1IKZF2GSPT1CYP2C19 | |
| SCHEMBL4449335 | 0.81 | CRBN (0.71) | CRBNCSNK1A1IKZF2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |