SCHEMBL30817433

SCHEMBL30817433

Brc1ccc2c(c1)c1ccccc1n2-c1cccc(-c2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
ATM Q13315 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TSPO P30536 3/20 0.38
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
HTT P42858 2/20 0.36
FAAH O00519 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PKM P14618 1/20 0.36
MGLL Q99685 1/20 0.36
RAD52 P43351 1/20 0.36
DCTPP1 Q9H773 1/20 0.35
MAPK1 P28482 1/20 0.35
HTR1A P08908 1/20 0.35
HTR7 P34969 1/20 0.35
IL1R1 P14778 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17379703 1.00 L3MBTL1 (0.47) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL26720834 0.99 L3MBTL1 (0.49) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL29616363 0.97 L3MBTL1 (0.50) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL14822296 0.97 L3MBTL1 (0.50) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL30250575 0.97 L3MBTL1 (0.50) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL23468855 0.96 L3MBTL1 (0.49) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL16731114 0.96 ATM (0.44) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL16731109 0.96 ATM (0.44) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL16605622 0.96 L3MBTL1 (0.47) L3MBTL1ATMKDM4ETSPOALDH1A1
SCHEMBL16731265 0.94 ATM (0.43) L3MBTL1ATMKDM4ETSPOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917906-B2 Compounds that can be used in an organic electronic device MERCK PATENT GMBH (DE) 2024-02-27 US disclosed