SCHEMBL30817779

SCHEMBL30817779

Ic1cccc(-c2noc(C3CCC3)n2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.65
SENP7 Q9BQF6 1/20 0.65
SENP6 Q9GZR1 1/20 0.65
PPARA Q07869 1/20 0.57
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GRM5 P41594 12/20 0.50
NR1H4 Q96RI1 1/20 0.50
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176845 1.00 CASP3 (0.65) CASP3SENP7SENP6PPARACA12
SCHEMBL29176859 0.94 CA12 (0.61) CASP3SENP7SENP6PPARACA12
SCHEMBL30817781 0.94 CA12 (0.61) CASP3SENP7SENP6PPARACA12
SCHEMBL16636594 0.80 CASP3 (0.69) CASP3SENP7SENP6PPARACA12
SCHEMBL60197 0.80 CASP3 (0.61) CASP3SENP7SENP6PPARACA12
SCHEMBL16636851 0.79 CASP3 (0.71) CASP3SENP7SENP6PPARACA12
SCHEMBL17014736 0.77 CYP1A2 (0.74) CASP3SENP7SENP6PPARACYP1A2
SCHEMBL59346 0.77 CASP3 (0.64) CASP3SENP7SENP6PPARACA12
SCHEMBL12377807 0.77 CASP3 (0.86) CASP3SENP7SENP6CA12CA1
SCHEMBL19399259 0.77 GRM5 (0.63) CASP3SENP7SENP6CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720535-B Pyrido [1, 2-a ] pyrimidine mesoionic derivative containing 1,2, 4-oxadiazole structure, and preparation and application thereof 贵州大学 2025-05-13 CN disclosed
CN-117720535-A Pyrido [1,2-a ] pyrimidine mesoionic derivative containing 1,2, 4-oxadiazole structure, and preparation and application thereof 贵州大学 2024-03-19 CN disclosed