Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 5/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819016 | 0.93 | GPR119 (0.44) | GPR119EGFRERBB3PIK3CBJAK2 | |
| SCHEMBL30818637 | 0.85 | NAMPT (0.47) | GPR119EGFRERBB3PIK3CBNAMPT | |
| SCHEMBL30818909 | 0.80 | GPR119 (0.47) | GPR119EGFRERBB3PIK3CBNPC1 | |
| SCHEMBL30818916 | 0.79 | PIK3CB (0.49) | EGFRERBB3PIK3CBNPC1ALDH1A1 | |
| SCHEMBL30818655 | 0.78 | PIK3CB (0.57) | EGFRERBB3PIK3CBNPC1ALDH1A1 | |
| SCHEMBL30818884 | 0.77 | PIK3CB (0.50) | EGFRERBB3PIK3CBNPC1ALDH1A1 | |
| SCHEMBL30818886 | 0.76 | GPR119 (0.46) | GPR119EGFRERBB3PIK3CBPIK3R1 | |
| SCHEMBL30818735 | 0.74 | PIK3CB (0.57) | EGFRERBB3PIK3CBNPC1ALDH1A1 | |
| SCHEMBL30818789 | 0.72 | GPR119 (0.47) | GPR119PIK3CBPIK3R1PIK3CAPIK3CD | |
| SCHEMBL28884915 | 0.71 | GPR119 (0.56) | GPR119TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587435-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024056077-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2024-03-21 | — | — | WO | disclosed |