SCHEMBL30818752

SCHEMBL30818752

c1nc(N[C@@H]2CCNC2)cc(N2CCOCC2)n1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 3/20 0.49
HRH3 Q9Y5N1 2/20 0.49
HRH2 P25021 1/20 0.49
PIK3CB P42338 1/20 0.47
NPC1 O15118 5/20 0.46
ALDH1A1 P00352 1/20 0.46
ATM Q13315 1/20 0.46
RAB9A P51151 5/20 0.44
EGFR P00533 2/20 0.44
ERBB3 P21860 2/20 0.44
ABL1 P00519 1/20 0.43
BCR P11274 1/20 0.43
CYP2C19 P33261 1/20 0.43
GAA P10253 1/20 0.42
KMO O15229 1/20 0.42
PRKCI P41743 1/20 0.42
SYK P43405 1/20 0.41
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30818620 0.93 IRAK4 (0.47) HRH4HRH3PIK3CBNPC1ALDH1A1
SCHEMBL30818737 0.92 PIK3CB (0.49) HRH4PIK3CBNPC1ALDH1A1ATM
SCHEMBL30818747 0.79 PIK3CB (0.46) HRH4PIK3CBNPC1ALDH1A1ATM
SCHEMBL30819005 0.78 PIK3CB (0.51) HRH4HRH3HRH2PIK3CBNPC1
SCHEMBL1775752 0.77 HRH4 (0.50) HRH4HRH3HRH2
SCHEMBL30818598 0.77 HRH4 (0.49) HRH4PIK3CBNPC1ALDH1A1ATM
SCHEMBL30818603 0.77 PIK3CB (0.58) HRH4PIK3CBNPC1ALDH1A1ATM
SCHEMBL30818892 0.77 PIK3CB (0.58) HRH4PIK3CBNPC1ALDH1A1ATM
SCHEMBL20576716 0.76 HRH3 (0.66) HRH4HRH3HRH2ALDH1A1CYP2C19
SCHEMBL20576715 0.76 HRH3 (0.66) HRH4HRH3HRH2ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
WO-2024056077-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2024-03-21 WO disclosed