SCHEMBL30818756

SCHEMBL30818756

N[C@@H]1CCCN(c2cccc(F)c2)C1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BPTF Q12830 1/20 0.58
DPP4 P27487 7/20 0.44
IDH2 P48735 1/20 0.42
PIM1 P11309 1/20 0.41
PIM3 Q86V86 1/20 0.41
PIM2 Q9P1W9 1/20 0.41
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40
NSD2 O96028 1/20 0.40
KHK P50053 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40
MAP4K1 Q92918 1/20 0.39
C1S P09871 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1349683 0.90 BPTF (0.66) BPTFHTR2AHTR2CHTR2BKHK
SCHEMBL1349684 0.90 BPTF (0.66) BPTFHTR2AHTR2CHTR2BKHK
SCHEMBL6485626 0.90 BPTF (0.66) BPTFHTR2AHTR2CHTR2BKHK
SCHEMBL9312444 0.81 NOTUM (0.54) DPP4PIM1PIM3PIM2KHK
SCHEMBL9310553 0.81 IDH2 (0.59) IDH2PIM1HTR2CHTT
SCHEMBL377392 0.80 BPTF (0.60) BPTFHTR2AHTR2CHTR2BHTT
SCHEMBL22581822 0.80 NOTUM (0.49) DPP4KDM4EHTT
SCHEMBL29991273 0.80 BPTF (0.60) BPTFHTR2AHTR2CHTR2BHTT
SCHEMBL16544563 0.80 NOTUM (0.49) DPP4KDM4EHTT
SCHEMBL16434664 0.80 NOTUM (0.49) DPP4KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
WO-2024056077-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2024-03-21 WO disclosed