Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.60 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377392 | 1.00 | BPTF (0.60) | BPTFVCPC1SSSTR2MLYCD | |
| Hydrochloric Acid SCHEMBL376509 | 0.98 | BPTF (0.59) | BPTFVCPC1SSSTR2MLYCD | |
| SCHEMBL1349683 | 0.90 | BPTF (0.66) | BPTFVCPC1SSSTR2MLYCD | |
| SCHEMBL1349684 | 0.90 | BPTF (0.66) | BPTFVCPC1SSSTR2MLYCD | |
| SCHEMBL6485626 | 0.90 | BPTF (0.66) | BPTFVCPC1SSSTR2MLYCD | |
| SCHEMBL10373948 | 0.82 | BPTF (0.54) | BPTFC1SMLYCDMEN1KMT2A | |
| SCHEMBL20699709 | 0.82 | BPTF (0.54) | BPTFC1SMLYCDMEN1KMT2A | |
| SCHEMBL22657436 | 0.82 | BPTF (0.56) | BPTFC1SMLYCDIDO1TDO2 | |
| SCHEMBL13035710 | 0.82 | BPTF (0.56) | BPTFC1SMLYCDIDO1TDO2 | |
| SCHEMBL5220630 | 0.81 | SSTR2 (0.44) | BPTFVCPSSTR2NPY5RHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332708-A1 | SULFONAMIDE COMPOUNDS AS CARDIAC SARCOMERE ACTIVATORS | CYTOKINETICS INC (US) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332708-A1 | SULFONAMIDE COMPOUNDS AS CARDIAC SARCOMERE ACTIVATORS | TNNT2, TNNI3, MYLK2 | BPTF 2891/4885VCP 765/4885C1S 4584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.