Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081882 | 0.85 | LMNA (0.45) | MC4RLMNATP53CACNA1G | |
| SCHEMBL3095808 | 0.84 | MC4R (0.79) | MC4R | |
| SCHEMBL6222879 | 0.77 | MC4R (0.54) | MC4R | |
| SCHEMBL3096153 | 0.76 | MC4R (0.66) | MC4R | |
| SCHEMBL3096150 | 0.76 | MC4R (0.66) | MC4R | |
| SCHEMBL3088810 | 0.74 | MC4R (0.62) | MC4R | |
| SCHEMBL3821506 | 0.74 | MC4R (0.62) | MC4R | |
| SCHEMBL3090273 | 0.72 | MC4R (1.00) | MC4R | |
| SCHEMBL3090277 | 0.71 | MC4R (0.41) | MC4R | |
| SCHEMBL3095697 | 0.71 | MC4R (0.65) | MC4RSCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790719-B2 | Modulators of melanocortin receptor | ORE PHARMACEUTICALS, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7365070-B2 | Modulators of melanocortin receptor | ORE PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20070293498-A1 | Modulators of melanocortin receptor | GENE LOGIC, INC. (US) | 2007-12-20 | — | — | US | disclosed |
| EP-1590338-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | Gene Logic Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20040147746-A1 | Modulators of melanocortin receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-07-29 | — | — | US | disclosed |
| WO-2004050610-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | GENE LOGIC INC. (US) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293498-A1 | Modulators of melanocortin receptor | MC4R, MC1R, MC5R | MC4R 1/4885LMNA 4128/4885TP53 3317/4885 |
| US-20040147746-A1 | Modulators of melanocortin receptor | MC1R, MC3R, MC5R | MC4R 4/4885LMNA 3822/4885TP53 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.