SCHEMBL30819680

SCHEMBL30819680

CC1(C)[C@@H]2[C@@H](C(=O)N[C@H](C#N)C[C@@H]3CCNC3=O)N(C(=O)CCc3cc(F)cc(F)c3)C[C@@H]21

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSV O60911 1/20 0.62
CYP3A4 P08684 1/20 0.62
CTSS P25774 1/20 0.62
CTSK P43235 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25757707 0.87 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL25757709 0.87 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL30819681 0.87
SCHEMBL25757716 0.85 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL25758173 0.85 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL24014439 0.85 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL25757729 0.85 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL25757728 0.85 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL25759021 0.85 CTSV (0.62) CTSVCYP3A4CTSSCTSK
SCHEMBL25757718 0.84 CTSV (0.60) CTSVCYP3A4CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086777-A2 COMPOUNDS AND METHODS FOR TREATING DISEASES CAUSED BY VIRUSES AND BACTERIA THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-04-25 WO disclosed