Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.61 |
| ▸ | KDR | P35968 | 9/20 | 0.58 |
| ▸ | RET | P07949 | 3/20 | 0.58 |
| ▸ | KIF5B | P33176 | 3/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168707 | 1.00 | EGFR (0.61) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL30820457 | 0.90 | EGFR (0.73) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL27152271 | 0.90 | EGFR (0.73) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL30820600 | 0.83 | FBP1 (0.62) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL29168723 | 0.83 | FBP1 (0.62) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL30820511 | 0.83 | EGFR (0.64) | EGFRKDRRETKIF5BERBB2 | |
| Hydrochloric Acid SCHEMBL28028746 | 0.81 | KDR (0.81) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL30822070 | 0.79 | EGFR (0.53) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL30820401 | 0.76 | NPC1 (0.70) | EGFRKDRRETKIF5BERBB2 | |
| SCHEMBL5864702 | 0.76 | EGFR (0.77) | EGFRKDRRETKIF5BERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | VORONOI INC. (KR) | 2024-07-25 | — | — | US | disclosed |
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | ERBB2, EGFR, ERBB3 | EGFR 2/4885KDR 24/4885RET 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.