Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.59 |
| ▸ | KDR | P35968 | 12/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.59 |
| ▸ | FLT1 | P17948 | 10/20 | 0.59 |
| ▸ | FLT4 | P35916 | 9/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | KIF5B | P33176 | 2/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 5/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | TEK | Q02763 | 2/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | CIT | O14578 | 1/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27148399 | 1.00 | EGFR (0.59) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL29168736 | 0.93 | EGFR (0.61) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL30820521 | 0.93 | EGFR (0.61) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL30030964 | 0.86 | EGFR (0.52) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL27154368 | 0.85 | EGFR (0.60) | EGFRERBB2RETEPHB4RIPK2 | |
| SCHEMBL27136126 | 0.84 | EGFR (0.58) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL4508831 | 0.81 | EGFR (0.74) | EGFRKDRFBP1ERBB2ERBB4 | |
| SCHEMBL30822092 | 0.81 | EGFR (0.56) | EGFRKDRERBB2RETEPHA2 | |
| SCHEMBL27136650 | 0.81 | EGFR (0.56) | EGFRKDRERBB2RETEPHA2 | |
| Hydrochloric Acid SCHEMBL4077165 | 0.81 | EGFR (0.74) | EGFRKDRFBP1ERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |