SCHEMBL30030964 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	EGFR	P00533	15/20	0.52

▸	KDR	P35968	9/20	0.51

▸	FGFR1	P11362	7/20	0.51

▸	FLT1	P17948	7/20	0.51

▸	FLT4	P35916	6/20	0.51

▸	ERBB2	P04626	5/20	0.51

▸	PDGFRB	P09619	2/20	0.51

▸	TEK	Q02763	2/20	0.51

▸	EPHA2	P29317	2/20	0.51

▸	EPHB4	P54760	2/20	0.51

▸	ERBB4	Q15303	2/20	0.51

▸	RET	P07949	2/20	0.51

▸	KIF5B	P33176	2/20	0.51

▸	BMPR1B	O00238	1/20	0.51

▸	PLK4	O00444	1/20	0.51

▸	CIT	O14578	1/20	0.51

▸	GAK	O14976	1/20	0.51

▸	EPHB6	O15197	1/20	0.51

▸	RIPK2	O43353	1/20	0.51

▸	ROCK2	O75116	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30032029	0.94	EGFR (0.58)	EGFRKDRFGFR1FLT1FLT4
SCHEMBL27154368	0.87	EGFR (0.60)	EGFRERBB2EPHB4RETRIPK2
SCHEMBL27136650	0.86	EGFR (0.56)	EGFRKDRERBB2EPHA2EPHB4
SCHEMBL30822092	0.86	EGFR (0.56)	EGFRKDRERBB2EPHA2EPHB4
SCHEMBL30820454	0.86	EGFR (0.59)	EGFRKDRFGFR1FLT1FLT4
SCHEMBL27148399	0.86	EGFR (0.59)	EGFRKDRFGFR1FLT1FLT4
SCHEMBL27152211	0.80	EGFR (0.62)	EGFRERBB2EPHA2EPHB4RET
SCHEMBL30820508	0.80	EGFR (0.62)	EGFRERBB2EPHA2EPHB4RET
SCHEMBL30031254	0.80	EGFR (0.52)	EGFRKDRFGFR1FLT1FLT4
SCHEMBL30820521	0.79	EGFR (0.61)	EGFRKDRFGFR1FLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022225238-A1	HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF	보로노이 주식회사	2022-10-27	—	—	WO	disclosed